Cargando…

Peptidomimetic inhibitor of L-plastin reduces osteoclastic bone resorption in aging female mice

L-plastin (LPL) was identified as a potential regulator of the actin-bundling process involved in forming nascent sealing zones (NSZs), which are precursor zones for mature sealing zones. TAT-fused cell-penetrating small molecular weight LPL peptide (TAT- MARGSVSDEE, denoted as an inhibitory LPL pep...

Descripción completa

Detalles Bibliográficos
Autores principales: Aljohani, Hanan, Stains, Joseph P., Majumdar, Sunipa, Srinivasan, Deepa, Senbanjo, Linda, Chellaiah, Meenakshi A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8035201/
https://www.ncbi.nlm.nih.gov/pubmed/33837180
http://dx.doi.org/10.1038/s41413-020-00135-9