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Peptidomimetic inhibitor of L-plastin reduces osteoclastic bone resorption in aging female mice
L-plastin (LPL) was identified as a potential regulator of the actin-bundling process involved in forming nascent sealing zones (NSZs), which are precursor zones for mature sealing zones. TAT-fused cell-penetrating small molecular weight LPL peptide (TAT- MARGSVSDEE, denoted as an inhibitory LPL pep...
Autores principales: | Aljohani, Hanan, Stains, Joseph P., Majumdar, Sunipa, Srinivasan, Deepa, Senbanjo, Linda, Chellaiah, Meenakshi A. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8035201/ https://www.ncbi.nlm.nih.gov/pubmed/33837180 http://dx.doi.org/10.1038/s41413-020-00135-9 |
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