Multinucleation associated DNA damage blocks proliferation in p53-compromised cells

Nuclear atypia is one of the hallmarks of cancers. Here, we perform single-cell tracking studies to determine the immediate and long-term impact of nuclear atypia. Tracking the fate of newborn cells exhibiting nuclear atypia shows that multinucleation, unlike other forms of nuclear atypia, blocks pr...

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Detalles Bibliográficos
Autores principales: Hart, Madeleine, Adams, Sophie D., Draviam, Viji M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8035210/
https://www.ncbi.nlm.nih.gov/pubmed/33837239
http://dx.doi.org/10.1038/s42003-021-01979-5

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8035210/
https://www.ncbi.nlm.nih.gov/pubmed/33837239
http://dx.doi.org/10.1038/s42003-021-01979-5

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