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Adenosine integrates light and sleep signalling for the regulation of circadian timing in mice

The accumulation of adenosine is strongly correlated with the need for sleep and the detection of sleep pressure is antagonised by caffeine. Caffeine also affects the circadian timing system directly and independently of sleep physiology, but how caffeine mediates these effects upon the circadian cl...

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Detalles Bibliográficos
Autores principales: Jagannath, Aarti, Varga, Norbert, Dallmann, Robert, Rando, Gianpaolo, Gosselin, Pauline, Ebrahimjee, Farid, Taylor, Lewis, Mosneagu, Dragos, Stefaniak, Jakub, Walsh, Steven, Palumaa, Teele, Di Pretoro, Simona, Sanghani, Harshmeena, Wakaf, Zeinab, Churchill, Grant C., Galione, Antony, Peirson, Stuart N., Boison, Detlev, Brown, Steven A., Foster, Russell G., Vasudevan, Sridhar R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8035342/
https://www.ncbi.nlm.nih.gov/pubmed/33837202
http://dx.doi.org/10.1038/s41467-021-22179-z