Kv1.1 deficiency alters repetitive and social behaviors in mice and rescues autistic‐like behaviors due to Scn2a haploinsufficiency

BACKGROUND: Autism spectrum disorder (ASD) and epilepsy are highly comorbid, suggesting potential overlap in genetic etiology, pathophysiology, and neurodevelopmental abnormalities; however, the nature of this relationship remains unclear. This work investigated how two ion channel mutations, one as...

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Detalles Bibliográficos
Autores principales: Indumathy, Jagadeeswaran, Pruitt, April, Gautier, Nicole M., Crane, Kaitlin, Glasscock, Edward
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8035482/
https://www.ncbi.nlm.nih.gov/pubmed/33484493
http://dx.doi.org/10.1002/brb3.2041

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8035482/
https://www.ncbi.nlm.nih.gov/pubmed/33484493
http://dx.doi.org/10.1002/brb3.2041

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