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Kv1.1 deficiency alters repetitive and social behaviors in mice and rescues autistic‐like behaviors due to Scn2a haploinsufficiency
BACKGROUND: Autism spectrum disorder (ASD) and epilepsy are highly comorbid, suggesting potential overlap in genetic etiology, pathophysiology, and neurodevelopmental abnormalities; however, the nature of this relationship remains unclear. This work investigated how two ion channel mutations, one as...
Autores principales: | Indumathy, Jagadeeswaran, Pruitt, April, Gautier, Nicole M., Crane, Kaitlin, Glasscock, Edward |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8035482/ https://www.ncbi.nlm.nih.gov/pubmed/33484493 http://dx.doi.org/10.1002/brb3.2041 |
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