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Long non-coding RNA GAS5 aggravates myocardial depression in mice with sepsis via the microRNA-449b/HMGB1 axis and the NF-κB signaling pathway

Sepsis is a common cause of deaths of patients in intensive care unit. The study aims to figure out the role of long non-coding RNA (lncRNA) GAS5 in the myocardial depression in mice with sepsis. Cecal ligation and puncture (CLP) was applied to induce sepsis in mice, and then the heart function, myo...

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Detalles Bibliográficos
Autores principales: Gao, Hongfeng, Ma, Huijing, Gao, Min, Chen, Aichun, Zha, Shujuan, Yan, Jixi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Portland Press Ltd. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8035624/
https://www.ncbi.nlm.nih.gov/pubmed/33645622
http://dx.doi.org/10.1042/BSR20201738