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Associations among phthalate exposure, DNA methylation of TSLP, and childhood allergy

BACKGROUND: Dysregulation of thymic stromal lymphopoietin (TSLP) expressions is linked to asthma and allergic disease. Exposure to phthalate esters, a widely used plasticizer, is associated with respiratory and allergic morbidity. Dibutyl phthalate (DBP) causes TSLP upregulation in the skin. In addi...

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Detalles Bibliográficos
Autores principales: Wang, Wan-Ru, Chen, Nai-Tzu, Hsu, Nai-Yun, Kuo, I-Ying, Chang, Hsin-Wen, Wang, Jiu-Yao, Su, Huey-Jen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8035749/
https://www.ncbi.nlm.nih.gov/pubmed/33836808
http://dx.doi.org/10.1186/s13148-021-01061-1