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Analytical validation of a real-time hydrolysis probe PCR assay for quantifying Plasmodium falciparum parasites in experimentally infected human adults

BACKGROUND: Volunteer infection studies have become a standard model for evaluating drug efficacy against Plasmodium infections. Molecular techniques such as qPCR are used in these studies due to their ability to provide robust and accurate estimates of parasitaemia at increased sensitivity compared...

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Detalles Bibliográficos
Autores principales: Wang, Claire Y. T., Ballard, Emma L., Pava, Zuleima, Marquart, Louise, Gaydon, Jane, Murphy, Sean C., Whiley, David, O’Rourke, Peter, McCarthy, James S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8035755/
https://www.ncbi.nlm.nih.gov/pubmed/33838672
http://dx.doi.org/10.1186/s12936-021-03717-y