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Mesenchymal stem cells accelerated growth and metastasis of neuroblastoma and preferentially homed towards both primary and metastatic loci in orthotopic neuroblastoma model

BACKGROUND: Majority of neuroblastoma patients develop metastatic disease at diagnosis and their prognosis is poor with current therapeutic approach. Major challenges are how to tackle the mechanisms responsible for tumorigenesis and metastasis. Human mesenchymal stem cells (hMSCs) may be actively i...

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Detalles Bibliográficos
Autores principales: Yu, Jiao-Le, Chan, Shing, Fung, Marcus Kwong-Lam, Chan, Godfrey Chi-Fung
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8035760/
https://www.ncbi.nlm.nih.gov/pubmed/33838662
http://dx.doi.org/10.1186/s12885-021-08090-2