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LINC00221 silencing prevents the progression of hepatocellular carcinoma through let-7a-5p-targeted inhibition of MMP11

BACKGROUND: Microarray profiles of hepatocellular carcinoma (HCC) identified that long intergenic noncoding RNA 00221 (LINC00221) was upregulated. Herein, we aimed to identify the functional significance and underlying mechanisms of LINC00221 in HCC. METHODS AND RESULTS: Human HCC samples had increa...

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Detalles Bibliográficos
Autores principales: Yang, Lin, Si, Hailong, Ma, Meng, Fang, Yu, Jiang, Yina, Wang, Jintao, Zhang, Cheng, Xiao, Haijuan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8035785/
https://www.ncbi.nlm.nih.gov/pubmed/33836753
http://dx.doi.org/10.1186/s12935-021-01819-w