The Effect of Alendronate on Osteoclastogenesis in Different Combinations of M-CSF and RANKL Growth Factors

Bisphosphonates (BPs) are compounds resembling the pyrophosphate structure. BPs bind the mineral component of bones. During the bone resorption by osteoclasts, nitrogen-containing BPs are released and internalized, causing an inhibition of the mevalonate pathway. As a consequence, osteoclasts are un...

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Detalles Bibliográficos
Autores principales: Hedvičáková, Věra, Žižková, Radmila, Buzgo, Matěj, Rampichová, Michala, Filová, Eva
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8035832/
https://www.ncbi.nlm.nih.gov/pubmed/33809737
http://dx.doi.org/10.3390/biom11030438

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8035832/
https://www.ncbi.nlm.nih.gov/pubmed/33809737
http://dx.doi.org/10.3390/biom11030438

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