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The Effect of Alendronate on Osteoclastogenesis in Different Combinations of M-CSF and RANKL Growth Factors

Bisphosphonates (BPs) are compounds resembling the pyrophosphate structure. BPs bind the mineral component of bones. During the bone resorption by osteoclasts, nitrogen-containing BPs are released and internalized, causing an inhibition of the mevalonate pathway. As a consequence, osteoclasts are un...

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Detalles Bibliográficos
Autores principales:	Hedvičáková, Věra, Žižková, Radmila, Buzgo, Matěj, Rampichová, Michala, Filová, Eva
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2021
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8035832/ https://www.ncbi.nlm.nih.gov/pubmed/33809737 http://dx.doi.org/10.3390/biom11030438

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