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Tau Is Truncated in Five Regions of the Normal Adult Human Brain

The truncation of Tau is thought to be important in promoting aggregation, with this feature characterising the pathology of dementias such as Alzheimer disease. Antibodies to the C-terminal and N-terminal regions of Tau were employed to examine Tau cleavage in five human brain regions: the entorhin...

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Detalles Bibliográficos
Autores principales: Friedrich, Michael G., Skora, Amanda, Hancock, Sarah E., Mitchell, Todd W., Else, Paul L., Truscott, Roger J. W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8036332/
https://www.ncbi.nlm.nih.gov/pubmed/33805376
http://dx.doi.org/10.3390/ijms22073521