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Exosomes from Plasma of Neuroblastoma Patients Contain Doublestranded DNA Reflecting the Mutational Status of Parental Tumor Cells

Neuroblastoma (NB) is an aggressive infancy tumor, leading cause of death among preschool age diseases. Here we focused on characterization of exosomal DNA (exo-DNA) isolated from plasma cell-derived exosomes of neuroblastoma patients, and its potential use for detection of somatic mutations present...

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Detalles Bibliográficos
Autores principales: Degli Esposti, Chiara, Iadarola, Barbara, Maestri, Simone, Beltrami, Cristina, Lavezzari, Denise, Morini, Martina, De Marco, Patrizia, Erminio, Giovanni, Garaventa, Alberto, Zara, Federico, Delledonne, Massimo, Ognibene, Marzia, Pezzolo, Annalisa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8036333/
https://www.ncbi.nlm.nih.gov/pubmed/33915956
http://dx.doi.org/10.3390/ijms22073667