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High ROS Production by Celecoxib and Enhanced Sensitivity for Death Ligand-Induced Apoptosis in Cutaneous SCC Cell Lines

Incidence of cutaneous squamous cell carcinoma (cSCC) and actinic keratosis has increased worldwide, and non-steroidal anti-inflammatory drugs as celecoxib are considered for treatment. We show here strong anti-proliferative effects of celecoxib in four cSCC cell lines, while apoptosis and cell viab...

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Detalles Bibliográficos
Autores principales: Zhu, Jiaqi, May, Stefanie, Ulrich, Claas, Stockfleth, Eggert, Eberle, Jürgen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8036359/
https://www.ncbi.nlm.nih.gov/pubmed/33807213
http://dx.doi.org/10.3390/ijms22073622