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Deciphering the Binding Interactions between Acinetobacter baumannii ACP and β-ketoacyl ACP Synthase III to Improve Antibiotic Targeting Using NMR Spectroscopy

Fatty acid synthesis is essential for bacterial viability. Thus, fatty acid synthases (FASs) represent effective targets for antibiotics. Nevertheless, multidrug-resistant bacteria, including the human opportunistic bacteria, Acinetobacter baumannii, are emerging threats. Meanwhile, the FAS pathway...

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Detalles Bibliográficos
Autores principales: Choi, Sungjae, Park, Jungwoo, Yeon, Jiwon, Jang, Ahjin, Lee, Woo Cheol, Kim, Yangmee
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8036411/
https://www.ncbi.nlm.nih.gov/pubmed/33805050
http://dx.doi.org/10.3390/ijms22073317