A 2-Benzylmalonate Derivative as STAT3 Inhibitor Suppresses Tumor Growth in Hepatocellular Carcinoma by Upregulating β-TrCP E3 Ubiquitin Ligase

The aberrant activation of a signal transducer and activator of transcription 3 (STAT3) restrains type I interferon (IFN) α/β-induced antiviral responses and is associated with the development of cancer. Designing specific STAT3 inhibitors will thus provide new options for use as IFN therapy. Herein...

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Detalles Bibliográficos
Autores principales: Peng, Ting, Wonganan, Orawan, Zhang, Zhonghui, Yu, Jialing, Xi, Ruiying, Cao, Yu, Suksamrarn, Apichart, Zhang, Guolin, Wang, Fei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8036434/
https://www.ncbi.nlm.nih.gov/pubmed/33805945
http://dx.doi.org/10.3390/ijms22073354

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8036434/
https://www.ncbi.nlm.nih.gov/pubmed/33805945
http://dx.doi.org/10.3390/ijms22073354

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