Combinatorial Use of Both Epigenetic and Non-Epigenetic Mechanisms to Efficiently Reactivate HIV Latency

The persistence of latent HIV provirus pools in different resting CD4+ cell subsets remains the greatest obstacle in the current efforts to treat and cure HIV infection. Recent efforts to purge out latently infected memory CD4+ T-cells using latency-reversing agents have failed in clinical trials. T...

Descripción completa

Detalles Bibliográficos
Autores principales: Hokello, Joseph, Sharma, Adhikarimayum Lakhikumar, Tyagi, Mudit
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8036438/
https://www.ncbi.nlm.nih.gov/pubmed/33918134
http://dx.doi.org/10.3390/ijms22073697

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8036438/
https://www.ncbi.nlm.nih.gov/pubmed/33918134
http://dx.doi.org/10.3390/ijms22073697

Ejemplares similares