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Combinatorial Use of Both Epigenetic and Non-Epigenetic Mechanisms to Efficiently Reactivate HIV Latency
The persistence of latent HIV provirus pools in different resting CD4+ cell subsets remains the greatest obstacle in the current efforts to treat and cure HIV infection. Recent efforts to purge out latently infected memory CD4+ T-cells using latency-reversing agents have failed in clinical trials. T...
Autores principales: | Hokello, Joseph, Sharma, Adhikarimayum Lakhikumar, Tyagi, Mudit |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8036438/ https://www.ncbi.nlm.nih.gov/pubmed/33918134 http://dx.doi.org/10.3390/ijms22073697 |
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