The Inhibitory Effects of Plant Derivate Polyphenols on the Main Protease of SARS Coronavirus 2 and Their Structure–Activity Relationship

The main protease (M(pro)) is a major protease having an important role in viral replication of the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), the novel coronavirus that caused the pandemic of 2020. Here, active M(pro) was obtained as a 34.5 kDa protein by overexpression in E. col...

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Detalles Bibliográficos
Autores principales: Nguyen, Thi Thanh Hanh, Jung, Jong-Hyun, Kim, Min-Kyu, Lim, Sangyong, Choi, Jae-Myoung, Chung, Byoungsang, Kim, Do-Won, Kim, Doman
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8036510/
https://www.ncbi.nlm.nih.gov/pubmed/33808054
http://dx.doi.org/10.3390/molecules26071924

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8036510/
https://www.ncbi.nlm.nih.gov/pubmed/33808054
http://dx.doi.org/10.3390/molecules26071924

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