Targeting the IL-6/STAT3 Signalling Cascade to Reverse Tamoxifen Resistance in Estrogen Receptor Positive Breast Cancer

SIMPLE SUMMARY: This study identifies the molecular mechanisms through which BQ323636.1 can enhance IL-6 and IL-6R expression, which leads to the activation of STAT3 and the development of tamoxifen resistance in ER+ breast cancer. We demonstrated a statistically significant association of IL-6R wit...

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Detalles Bibliográficos
Autores principales: Tsoi, Ho, Man, Ellen P. S., Chau, Ka Man, Khoo, Ui-Soon
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8036560/
https://www.ncbi.nlm.nih.gov/pubmed/33806019
http://dx.doi.org/10.3390/cancers13071511

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8036560/
https://www.ncbi.nlm.nih.gov/pubmed/33806019
http://dx.doi.org/10.3390/cancers13071511

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