HDAC6 Signaling at Primary Cilia Promotes Proliferation and Restricts Differentiation of Glioma Cells

SIMPLE SUMMARY: Glioblastoma is the most common and lethal brain tumor in adults because it becomes resistant to virtually every treatment. Histone deacetylase 6 (HDAC6), which is located primarily in the cytoplasm, has a unique role in promoting the disassembly of cells’ primary cilium, a non-motil...

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Detalles Bibliográficos
Autores principales: Shi, Ping, Hoang-Minh, Lan B., Tian, Jia, Cheng, Alice, Basrai, Reemsha, Kalaria, Neil, Lebowitz, Joseph J., Khoshbouei, Habibeh, Deleyrolle, Loic P., Sarkisian, Matthew R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8036575/
https://www.ncbi.nlm.nih.gov/pubmed/33915983
http://dx.doi.org/10.3390/cancers13071644

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8036575/
https://www.ncbi.nlm.nih.gov/pubmed/33915983
http://dx.doi.org/10.3390/cancers13071644

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