Cargando…
HDAC6 Signaling at Primary Cilia Promotes Proliferation and Restricts Differentiation of Glioma Cells
SIMPLE SUMMARY: Glioblastoma is the most common and lethal brain tumor in adults because it becomes resistant to virtually every treatment. Histone deacetylase 6 (HDAC6), which is located primarily in the cytoplasm, has a unique role in promoting the disassembly of cells’ primary cilium, a non-motil...
Autores principales: | Shi, Ping, Hoang-Minh, Lan B., Tian, Jia, Cheng, Alice, Basrai, Reemsha, Kalaria, Neil, Lebowitz, Joseph J., Khoshbouei, Habibeh, Deleyrolle, Loic P., Sarkisian, Matthew R. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2021
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8036575/ https://www.ncbi.nlm.nih.gov/pubmed/33915983 http://dx.doi.org/10.3390/cancers13071644 |
Ejemplares similares
-
Glioma cell proliferation is enhanced in the presence of tumor-derived cilia vesicles
por: Hoang-Minh, Lan B., et al.
Publicado: (2018) -
Cilia at the Crossroads of Tumor Treating Fields and Chemotherapy
por: Deleyrolle, Loic P., et al.
Publicado: (2023) -
Tumor Treating Fields Suppression of Ciliogenesis Enhances Temozolomide Toxicity
por: Shi, Ping, et al.
Publicado: (2022) -
Increasing Ciliary ARL13B Expression Drives Active and Inhibitor-Resistant Smoothened and GLI into Glioma Primary Cilia
por: Shi, Ping, et al.
Publicado: (2023) -
Emerging Roles of Primary Cilia in Glioma
por: Sarkisian, Matthew R., et al.
Publicado: (2019)