Covalent Bi-Modular Parallel and Antiparallel G-Quadruplex DNA Nanocostructs Reduce Viability of Patient Glioma Primary Cell Cultures

G-quadruplex oligonucleotides (GQs) exhibit specific anti-proliferative activity in human cancer cell lines, and they can selectively inhibit the viability/proliferation of cancer cell lines vs. non-cancer ones. This ability could be translated into a cancer treatment, in particular for glioblastoma...

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Detalles Bibliográficos
Autores principales: Legatova, Valeria, Samoylenkova, Nadezhda, Arutyunyan, Alexander, Tashlitsky, Vadim, Zavyalova, Elena, Usachev, Dmitry, Pavlova, Galina, Kopylov, Alexey
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8036578/
https://www.ncbi.nlm.nih.gov/pubmed/33806042
http://dx.doi.org/10.3390/ijms22073372

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8036578/
https://www.ncbi.nlm.nih.gov/pubmed/33806042
http://dx.doi.org/10.3390/ijms22073372

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