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Covalent Bi-Modular Parallel and Antiparallel G-Quadruplex DNA Nanocostructs Reduce Viability of Patient Glioma Primary Cell Cultures
G-quadruplex oligonucleotides (GQs) exhibit specific anti-proliferative activity in human cancer cell lines, and they can selectively inhibit the viability/proliferation of cancer cell lines vs. non-cancer ones. This ability could be translated into a cancer treatment, in particular for glioblastoma...
Autores principales: | Legatova, Valeria, Samoylenkova, Nadezhda, Arutyunyan, Alexander, Tashlitsky, Vadim, Zavyalova, Elena, Usachev, Dmitry, Pavlova, Galina, Kopylov, Alexey |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8036578/ https://www.ncbi.nlm.nih.gov/pubmed/33806042 http://dx.doi.org/10.3390/ijms22073372 |
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