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Between a Rock and a Hard Place: An Epigenetic-Centric View of Testicular Germ Cell Tumors

SIMPLE SUMMARY: This minireview focuses on the role of epigenetics in testicular cancer. A working model is developed that postulates that epigenetic features that drive testicular cancer malignancy also enable these tumors to be cured at a high rate with chemotherapy. Chemoresistance may occur by e...

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Detalles Bibliográficos
Autores principales: Singh, Ratnakar, Fazal, Zeeshan, Freemantle, Sarah J., Spinella, Michael J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8036638/
https://www.ncbi.nlm.nih.gov/pubmed/33805941
http://dx.doi.org/10.3390/cancers13071506