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Cardiac Oxidative Signaling and Physiological Hypertrophy in the Na/K-ATPase α1(s/s)α2(s/s) Mouse Model of High Affinity for Cardiotonic Steroids
The Na/K-ATPase is the specific receptor for cardiotonic steroids (CTS) such as ouabain and digoxin. At pharmacological concentrations used in the treatment of cardiac conditions, CTS inhibit the ion-pumping function of Na/K-ATPase. At much lower concentrations, in the range of those reported for en...
Autores principales: | , , , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8036649/ https://www.ncbi.nlm.nih.gov/pubmed/33801629 http://dx.doi.org/10.3390/ijms22073462 |