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Cardiac Oxidative Signaling and Physiological Hypertrophy in the Na/K-ATPase α1(s/s)α2(s/s) Mouse Model of High Affinity for Cardiotonic Steroids

The Na/K-ATPase is the specific receptor for cardiotonic steroids (CTS) such as ouabain and digoxin. At pharmacological concentrations used in the treatment of cardiac conditions, CTS inhibit the ion-pumping function of Na/K-ATPase. At much lower concentrations, in the range of those reported for en...

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Detalles Bibliográficos
Autores principales: Marck, Pauline V., Pessoa, Marco T., Xu, Yunhui, Kutz, Laura C., Collins, Dominic M., Yan, Yanling, King, Cierra, Wang, Xiaoliang, Duan, Qiming, Cai, Liquan, Xie, Jeffrey X., Lingrel, Jerry B., Xie, Zijian, Tian, Jiang, Pierre, Sandrine V.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8036649/
https://www.ncbi.nlm.nih.gov/pubmed/33801629
http://dx.doi.org/10.3390/ijms22073462