Breast Cancer Patient Prognosis Is Determined by the Interplay between TP53 Mutation and Alternative Transcript Expression: Insights from TP53 Long Amplicon Digital PCR Assays

SIMPLE SUMMARY: The TP53 gene, the most commonly mutated gene in human cancers, is capable of producing multiple RNAs (transcripts). The aim of our study was to measure the abundance of each TP53 transcript, combined with TP53 gene mutation information, to determine the interplay between these in a...

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Detalles Bibliográficos
Autores principales: Lasham, Annette, Knowlton, Nicholas, Mehta, Sunali Y., Braithwaite, Antony W., Print, Cristin G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8036703/
https://www.ncbi.nlm.nih.gov/pubmed/33810361
http://dx.doi.org/10.3390/cancers13071531

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8036703/
https://www.ncbi.nlm.nih.gov/pubmed/33810361
http://dx.doi.org/10.3390/cancers13071531

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