Inhibition of Soluble Epoxide Hydrolase Ameliorates Phenotype and Cognitive Abilities in a Murine Model of Niemann Pick Type C Disease

Niemann–Pick type C (NPC) disease is a rare autosomal recessive inherited childhood neurodegenerative disease characterized by the accumulation of cholesterol and glycosphingolipids, involving the autophagy-lysosome system. Inhibition of soluble epoxide hydrolase (sEH), an enzyme that metabolizes ep...

Descripción completa

Detalles Bibliográficos
Autores principales: Griñán-Ferré, Christian, Companys-Alemany, Júlia, Jarné-Ferrer, Júlia, Codony, Sandra, González-Castillo, Celia, Ortuño-Sahagún, Daniel, Vilageliu, Lluïsa, Grinberg, Daniel, Vázquez, Santiago, Pallàs, Mercè
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8036710/
https://www.ncbi.nlm.nih.gov/pubmed/33810307
http://dx.doi.org/10.3390/ijms22073409

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8036710/
https://www.ncbi.nlm.nih.gov/pubmed/33810307
http://dx.doi.org/10.3390/ijms22073409

Ejemplares similares