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Two Be or Not Two Be: The Nuclear Autoantigen La/SS-B Is Able to Form Dimers and Oligomers in a Redox Dependent Manner

According to the literature, the autoantigen La is involved in Cap-independent translation. It was proposed that one prerequisite for this function is the formation of a protein dimer. However, structural analyses argue against La protein dimers. Noteworthy to mention, these structural analyses were...

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Detalles Bibliográficos
Autores principales: Berndt, Nicole, Bippes, Claudia C., Michalk, Irene, Bachmann, Dominik, Bachmann, Jennifer, Puentes-Cala, Edinson, Bartsch, Tabea, Loureiro, Liliana R., Kegler, Alexandra, Bergmann, Ralf, Gross, Joanne K., Gross, Tim, Kurien, Biji T., Scofield, R. Hal, Farris, A. Darise, James, Judith A., Schmitz, Marc, Fahmy, Karim, Feldmann, Anja, Arndt, Claudia, Bachmann, Michael P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8036718/
https://www.ncbi.nlm.nih.gov/pubmed/33806091
http://dx.doi.org/10.3390/ijms22073377