Targeting Feedforward Loops Formed by Nuclear Receptor RORγ and Kinase PBK in mCRPC with Hyperactive AR Signaling

SIMPLE SUMMARY: Prostate cancer is one of the most frequently diagnosed cancers in men and is the second leading cause of cancer death in developed countries. Current therapeutics that target the androgen receptor (AR) are only transiently effective. Anti-AR therapy-resistant tumors often emerge wit...

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Detalles Bibliográficos
Autores principales: Zhang, Xiong, Huang, Zenghong, Wang, Junjian, Ma, Zhao, Yang, Joy, Corey, Eva, Evans, Christopher P., Yu, Ai-Ming, Chen, Hong-Wu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8036795/
https://www.ncbi.nlm.nih.gov/pubmed/33916325
http://dx.doi.org/10.3390/cancers13071672

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8036795/
https://www.ncbi.nlm.nih.gov/pubmed/33916325
http://dx.doi.org/10.3390/cancers13071672

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