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Targeting Feedforward Loops Formed by Nuclear Receptor RORγ and Kinase PBK in mCRPC with Hyperactive AR Signaling
SIMPLE SUMMARY: Prostate cancer is one of the most frequently diagnosed cancers in men and is the second leading cause of cancer death in developed countries. Current therapeutics that target the androgen receptor (AR) are only transiently effective. Anti-AR therapy-resistant tumors often emerge wit...
Autores principales: | Zhang, Xiong, Huang, Zenghong, Wang, Junjian, Ma, Zhao, Yang, Joy, Corey, Eva, Evans, Christopher P., Yu, Ai-Ming, Chen, Hong-Wu |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8036795/ https://www.ncbi.nlm.nih.gov/pubmed/33916325 http://dx.doi.org/10.3390/cancers13071672 |
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