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Chromatin Regulator SPEN/SHARP in X Inactivation and Disease

SIMPLE SUMMARY: Carcinogenesis is a multistep process involving not only the activation of oncogenes and disabling tumor suppressor genes, but also epigenetic modulation of gene expression. X chromosome inactivation (XCI) is a paradigm to study heterochromatin formation and maintenance. The double d...

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Detalles Bibliográficos
Autores principales: Giaimo, Benedetto Daniele, Robert-Finestra, Teresa, Oswald, Franz, Gribnau, Joost, Borggrefe, Tilman
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8036811/
https://www.ncbi.nlm.nih.gov/pubmed/33916248
http://dx.doi.org/10.3390/cancers13071665