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Investigation of the Interaction of Human Origin Recognition Complex Subunit 1 with G-Quadruplex DNAs of Human c-myc Promoter and Telomere Regions

Origin recognition complex (ORC) binds to replication origins in eukaryotic DNAs and plays an important role in replication. Although yeast ORC is known to sequence-specifically bind to a replication origin, how human ORC recognizes a replication origin remains unknown. Previous genome-wide studies...

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Detalles Bibliográficos
Autores principales: Eladl, Afaf, Yamaoki, Yudai, Hoshina, Shoko, Horinouchi, Haruka, Kondo, Keiko, Waga, Shou, Nagata, Takashi, Katahira, Masato
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8036949/
https://www.ncbi.nlm.nih.gov/pubmed/33801762
http://dx.doi.org/10.3390/ijms22073481