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HIF-1α and Pro-Inflammatory Signaling Improves the Immunomodulatory Activity of MSC-Derived Extracellular Vesicles

Despite the strong evidence for the immunomodulatory activity of mesenchymal stromal cells (MSCs), clinical trials have so far failed to clearly show benefit, likely reflecting methodological shortcomings and lack of standardization. MSC-mediated tissue repair is commonly believed to occur in a para...

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Detalles Bibliográficos
Autores principales: Gómez-Ferrer, Marta, Villanueva-Badenas, Estela, Sánchez-Sánchez, Rafael, Sánchez-López, Christian M., Baquero, Maria Carmen, Sepúlveda, Pilar, Dorronsoro, Akaitz
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8036951/
https://www.ncbi.nlm.nih.gov/pubmed/33810359
http://dx.doi.org/10.3390/ijms22073416