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Assessment of γ-H2AX and 53BP1 Foci in Peripheral Blood Lymphocytes to Predict Subclinical Hematotoxicity and Response in Somatostatin Receptor-Targeted Radionuclide Therapy for Advanced Gastroenteropancreatic Neuroendocrine Tumors

SIMPLE SUMMARY: Assessment of the radiation-induced alterations in peripheral blood lymphocytes is a validated strategy for biological dosimetry and assessment of individual radiosensitivity. However, its clinical significance as a liquid biopsy for predicting hematotoxicity and treatment response w...

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Detalles Bibliográficos
Autores principales: Derlin, Thorsten, Bogdanova, Natalia, Ohlendorf, Fiona, Ramachandran, Dhanya, Werner, Rudolf A., Ross, Tobias L., Christiansen, Hans, Bengel, Frank M., Henkenberens, Christoph
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8036952/
https://www.ncbi.nlm.nih.gov/pubmed/33806081
http://dx.doi.org/10.3390/cancers13071516