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The PI3Kδ Inhibitor Idelalisib Diminishes Platelet Function and Shows Antithrombotic Potential

Background: Clinical management of ischemic events and prevention of vascular disease is based on antiplatelet drugs. Given the relevance of phosphatidylinositol-4,5-bisphosphate 3-kinase (PI3K) as a candidate target in thrombosis, the main goal of the present study was to identify novel antiplatele...

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Detalles Bibliográficos
Autores principales: Barrachina, María N., Izquierdo, Irene, Hermida-Nogueira, Lidia, Morán, Luis A., Pérez, Amparo, Arroyo, Ana B., García-Barberá, Nuria, González-Conejero, Rocío, Troitiño, Sara, Eble, Johannes A., Rivera, José, Martínez, Constantino, Loza, María I., Domínguez, Eduardo, García, Ángel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8037016/
https://www.ncbi.nlm.nih.gov/pubmed/33804911
http://dx.doi.org/10.3390/ijms22073304