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The Winged Helix Domain of CSB Regulates RNAPII Occupancy at Promoter Proximal Pause Sites

Cockayne syndrome group B protein (CSB), a member of the SWI/SNF superfamily, resides in an elongating RNA polymerase II (RNAPII) complex and regulates transcription elongation. CSB contains a C-terminal winged helix domain (WHD) that binds to ubiquitin and plays an important role in DNA repair. How...

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Detalles Bibliográficos
Autores principales: Batenburg, Nicole L., Cui, Shixin, Walker, John R., Schellhorn, Herb E., Zhu, Xu-Dong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8037043/
https://www.ncbi.nlm.nih.gov/pubmed/33806087
http://dx.doi.org/10.3390/ijms22073379