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Structural Basis for the Function of the C-Terminal Proton Release Pathway in the Calcium Pump
The calcium pump (sarco/endoplasmic reticulum Ca(2+)-ATPase, SERCA) plays a major role in calcium homeostasis in muscle cells by clearing cytosolic Ca(2+) during muscle relaxation. Active Ca(2+) transport by SERCA involves the structural transition from a low-Ca(2+) affinity E2 state toward a high-C...
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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MDPI
2021
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8037123/ https://www.ncbi.nlm.nih.gov/pubmed/33805255 http://dx.doi.org/10.3390/ijms22073507 |