O-GlcNAcylation and O-GlcNAc Cycling Regulate Gene Transcription: Emerging Roles in Cancer

SIMPLE SUMMARY: O-linked β-N-acetylglucosamine (O-GlcNAc) is a post-translational modification (PTM) linking nutrient flux through the hexosamine biosynthetic pathway (HBP) to gene transcription. Mounting experimental and clinical data implicates aberrant O-GlcNAcylation in the development and progr...

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Detalles Bibliográficos
Autores principales: Parker, Matthew P., Peterson, Kenneth R., Slawson, Chad
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8037238/
https://www.ncbi.nlm.nih.gov/pubmed/33916244
http://dx.doi.org/10.3390/cancers13071666

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8037238/
https://www.ncbi.nlm.nih.gov/pubmed/33916244
http://dx.doi.org/10.3390/cancers13071666

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