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O-GlcNAcylation and O-GlcNAc Cycling Regulate Gene Transcription: Emerging Roles in Cancer

SIMPLE SUMMARY: O-linked β-N-acetylglucosamine (O-GlcNAc) is a post-translational modification (PTM) linking nutrient flux through the hexosamine biosynthetic pathway (HBP) to gene transcription. Mounting experimental and clinical data implicates aberrant O-GlcNAcylation in the development and progr...

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Detalles Bibliográficos
Autores principales:	Parker, Matthew P., Peterson, Kenneth R., Slawson, Chad
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2021
Materias:	Review
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8037238/ https://www.ncbi.nlm.nih.gov/pubmed/33916244 http://dx.doi.org/10.3390/cancers13071666

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