An Activatable T(1)-Weighted MR Contrast Agent: A Noninvasive Tool for Tracking the Vicinal Thiol Motif of Thioredoxin in Live Cells

We have synthesized new magnetic resonance imaging (MRI) T(1) contrast agents (CA1 and CA2) that permit the activatable recognition of the cellular vicinal thiol motifs of the protein thioredoxin. The contrast agents showed MR relaxivities typical of gadolinium complexes with a single water molecule...

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Detalles Bibliográficos
Autores principales: Kang, Jongeun, Hwang, Eunha, Lee, Hyunseung, Cho, Mi Young, Karan, Sanu, Kim, Hak Nam, Kim, Jong Seung, Sessler, Jonathan L., Bhuniya, Sankarprasad, Hong, Kwan Soo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8037249/
https://www.ncbi.nlm.nih.gov/pubmed/33916181
http://dx.doi.org/10.3390/molecules26072018

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8037249/
https://www.ncbi.nlm.nih.gov/pubmed/33916181
http://dx.doi.org/10.3390/molecules26072018

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