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Long-Term Iron Deficiency and Dietary Iron Excess Exacerbate Acute Dextran Sodium Sulphate-Induced Colitis and Are Associated with Significant Dysbiosis

Background: Oral iron supplementation causes gastrointestinal side effects. Short-term alterations in dietary iron exacerbate inflammation and alter the gut microbiota, in murine models of colitis. Patients typically take supplements for months. We investigated the impact of long-term changes in die...

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Detalles Bibliográficos
Autores principales: Mahalhal, Awad, Burkitt, Michael D., Duckworth, Carrie A., Hold, Georgina L., Campbell, Barry J., Pritchard, David Mark, Probert, Chris S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8037348/
https://www.ncbi.nlm.nih.gov/pubmed/33807459
http://dx.doi.org/10.3390/ijms22073646