A Highly Selective In Vitro JNK3 Inhibitor, FMU200, Restores Mitochondrial Membrane Potential and Reduces Oxidative Stress and Apoptosis in SH-SY5Y Cells

Current treatments for neurodegenerative diseases (ND) are symptomatic and do not affect disease progression. Slowing this progression remains a crucial unmet need for patients and their families. c-Jun N-terminal kinase 3 (JNK3) are related to several ND hallmarks including apoptosis, oxidative str...

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Detalles Bibliográficos
Autores principales: Rehfeldt, Stephanie Cristine Hepp, Laufer, Stefan, Goettert, Márcia Inês
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8037381/
https://www.ncbi.nlm.nih.gov/pubmed/33918172
http://dx.doi.org/10.3390/ijms22073701

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8037381/
https://www.ncbi.nlm.nih.gov/pubmed/33918172
http://dx.doi.org/10.3390/ijms22073701

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