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Type III TGF-β Receptor Down-Regulation Promoted Tumor Progression via Complement Component C5a Induction in Hepatocellular Carcinoma

SIMPLE SUMMARY: The clinical implications of TGFβR3 downregulation are currently unknown in hepatocellular carcinoma (HCC). Clinically, we identified that HCC patients with low expression levels of tumoral TGFβR3 exhibited significantly late tumor stages and shortened survival outcomes. Moreover, HC...

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Detalles Bibliográficos
Autores principales: Yeung, Oscar Wai Ho, Qi, Xiang, Pang, Li, Liu, Hui, Ng, Kevin Tak Pan, Liu, Jiang, Lo, Chung Mau, Man, Kwan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8037431/
https://www.ncbi.nlm.nih.gov/pubmed/33805946
http://dx.doi.org/10.3390/cancers13071503