Methiothepin Increases Chemotherapy Efficacy against Resistant Melanoma Cells

We previously reported that methiothepin, a small molecule known as a nonselective serotonin 5-HT receptor antagonist, inhibited the doxorubicin efflux activity of the Hedgehog receptor Ptch1 and enhanced the cytotoxic, pro-apoptotic, anti-proliferative, and anti-clonogenic effects of doxorubicin on...

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Detalles Bibliográficos
Autores principales: Durand, Nelly, Simsir, Méliné, Signetti, Laurie, Labbal, Fabien, Ballotti, Robert, Mus-Veteau, Isabelle
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8037503/
https://www.ncbi.nlm.nih.gov/pubmed/33810240
http://dx.doi.org/10.3390/molecules26071867

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8037503/
https://www.ncbi.nlm.nih.gov/pubmed/33810240
http://dx.doi.org/10.3390/molecules26071867

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