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Clinical Activity of an hTERT-Specific Cancer Vaccine (Vx-001) in “Immune Desert” NSCLC

SIMPLE SUMMARY: We investigated whether there is any correlation between Vx-001 clinical activity and the tumor immune microenvironment (TIME). Our hypothesis was that Vx-001 should be clinically effective in patients with tumor-infiltrating lymphocyte (TIL) negative/low infiltrated (non-immunogenic...

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Detalles Bibliográficos
Autores principales: Pateras, Ioannis S., Kotsakis, Athanasios, Avgeris, Margaritis, Baliou, Evangelia, Kouroupakis, Panagiotis, Patsea, Eleni, Georgoulias, Vassilis, Menez-Jamet, Jeanne, Kinet, Jean-Pierre, Kosmatopoulos, Kostas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8037524/
https://www.ncbi.nlm.nih.gov/pubmed/33916194
http://dx.doi.org/10.3390/cancers13071658