Dysregulation of the Ubiquitin Proteasome System in Human Malignancies: A Window for Therapeutic Intervention

SIMPLE SUMMARY: The ubiquitin proteasome system (UPS) governs the non-lysosomal degradation of oxidized, damaged, or misfolded proteins in eukaryotic cells. Dysregulation of the UPS results in loss of ability to maintain protein quality through proteolysis, and is closely related to the development...

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Detalles Bibliográficos
Autores principales: Fhu, Chee Wai, Ali, Azhar
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8037609/
https://www.ncbi.nlm.nih.gov/pubmed/33805973
http://dx.doi.org/10.3390/cancers13071513

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8037609/
https://www.ncbi.nlm.nih.gov/pubmed/33805973
http://dx.doi.org/10.3390/cancers13071513

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