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Gene Transactivation and Transrepression in MYC-Driven Cancers

MYC is a proto-oncogene regulating a large number of genes involved in a plethora of cellular functions. Its deregulation results in activation of MYC gene expression and/or an increase in MYC protein stability. MYC overexpression is a hallmark of malignant growth, inducing self-renewal of stem cell...

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Detalles Bibliográficos
Autores principales: Scafuro, Marika, Capasso, Lucia, Carafa, Vincenzo, Altucci, Lucia, Nebbioso, Angela
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8037706/
https://www.ncbi.nlm.nih.gov/pubmed/33801599
http://dx.doi.org/10.3390/ijms22073458